Transcriptome and Histopathological Changes in Mouse Brain Infected with Neospora caninum

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Transcriptome and Histopathological Changes in Mouse Brain Infected with Neospora caninum

Neospora caninum is a protozoan parasite that causes neurological disorders in dogs and cattle. It can cause nonsuppurative meningoencephalitis and a variety of neuronal symptoms are observed, particularly in dogs. However, the pathogenic mechanism, including the relationship between the parasite distribution and the clinical signs, is unclear. In this study, to understand the pathogenic mechan...

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Evaluation of Cross Immunity and Histopathological Findings in Experimentally Infected BALB/c Mice with Neospora caninum and Besnoitia caprae

BACKGROUND Caprine besnoitiosis is an economically important disease of goats. Neospora caninum, another coccidian parasite of worldwide distribution, infects several animal species and is a major cause of abortion in cattle. Combined infections of N. caninum and Besnoitia caprae can occur in geographical areas endemic for both species of parasite in goats. This experiment was conducted to inve...

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Neospora caninum and neosporosis

Neospora caninum is a protozoan cyst forming apicomplexan parasite that causes neosporosis, notably in cattle (Bos taurus) and domestic dogs (Canis familiaris) [1,2]. It is closely related to Toxoplasma gondii and has emerged as a major cause of reproductive failure in cattle worldwide [2]. The parasite was first described in a dog with encephalomyelitis and myositis [1] and was later described...

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Neospora caninum and Wildlife

Bovine neosporosis caused by Neospora caninum is among the main causes of abortion in cattle nowadays. At present there is no effective treatment or vaccine. Serological evidence in domestic, wild, and zoo animals indicates that many species have been exposed to this parasite. However, many aspects of the life cycle of N. caninum are unknown and the role of wildlife in the life cycle of N. cani...

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evaluation of cross immunity and histopathological findings in experimentally infected balb/c mice with neospora caninum and besnoitia caprae.

background: caprine besnoitiosis is an economically important disease of goats. neospora caninum, another coccidian parasite of worldwide distribution, infects several animal species and is a major cause of abortion in cattle . combined infections of n. caninum and besnoitia caprae can occur in geo-graphical areas endemic for both species of parasite in goats. this experiment was conducted to i...

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ژورنال

عنوان ژورنال: Scientific Reports

سال: 2015

ISSN: 2045-2322

DOI: 10.1038/srep07936